Nonsteroidal anti-inflammatory drugs in community-acquired pneumonia

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Nonsteroidal anti-inflammatory drugs in community-acquired pneumonia.

One of the referenced articles, a study conducted by the editorial authors, was a retrospective case note review of 106 patients over a 12-year period, 20 of whom had been prescribed NSAIDs [3]. The explanations offered for the findings were two-fold: 1) that the administration of NSAIDs delayed antibiotic prescription, although this observed trend did not reach statistical significance in thei...

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Nonsteroidal anti-inflammatory drugs in orthopaedics.

It is important for orthopaedic surgeons to understand the role of prostaglandins in bone physiology and the mechanism of action of nonsteroidal anti-inflammatory drugs and their role in fracture healing, fusion, osteointegration, and aseptic loosening. Nonsteroidal anti-inflammatory drugs have benefits and risks in orthopaedic use, and their effects should be considered.

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Vigilance in Prescribing Nonsteroidal Anti-inflammatory Drugs

To the Editor: We read with great interest the article entitled, “A Case of Acute Myocardial Infarction Induced by Selective Cyclooxygenase-2 Inhibitor” by Seo et al.[1] The authors have shown a correlation of aceclofenac intake with the myocardial infarction. This is really important information to be noted as aceclofenac or any nonsteroidal anti-inflammatory drugs (NSAIDS) of this group were ...

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Nonsteroidal Anti-Inflammatory Drugs and the Kidney

Non-steroidal anti-inflammatory drugs (NSAIDs) inhibit the isoenzymes COX-1 and COX-2 of cyclooxygenase (COX). Renal side effects (e.g., kidney function, fluid and urinary electrolyte excretion) vary with the extent of COX-2-COX-1 selectivity and the administered dose of these compounds. While young healthy subjects will rarely experience adverse renal effects with the use of NSAIDs, elderly pa...

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ژورنال

عنوان ژورنال: European Respiratory Journal

سال: 2015

ISSN: 0903-1936,1399-3003

DOI: 10.1183/09031936.00048715